Hot selling high quality 2-Bromo-1-phenyl-1-pentanone CAS 49851-31-2 Security Customs Factory direct sales factory large stock Pharmaceutical intermediate

2-bromo-1-phenyl-1-pentanone is a derivative of valerone. It can be used as pharmaceutical intermediates.

At room temperature, 16.2g (0.1mol) of phenopentanone and 30.9g (0.3mol) of sodium bromide were added into a 500mL round-bottomed flask, and after stirring well, 24g (0.2mol) of 30% hydrochloric acid was added, and 19g (0.15mol) of 30% hydrogen peroxide was slowly added. After the drop, the reaction was continued for 1~2 hours. After the reaction was monitored by TLC, the stirring was stopped and stratified, washed with saturated sodium carbonate and saturated salt water respectively, combined with organic phase, concentrated and dried with anhydrous magnesium sulfate to obtain 2-bromo-1-phenyl-1-pentanone, a bright yellow oily liquid with 95% yield and 98% purity