What is Procaine?
2024-08-14
| Common Name | Procaine |
|---|---|
| CAS Number | 59-46-1 |
| Molecular Weight | 236.310 |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 373.6±22.0 °C at 760 mmHg |
| Melting point | 61ºC |
| Molecular Formula | C13H20N2O2 |
| Flash Point | 179.8±22.3 °C |
| Exact Mass | 236.152481 |
| PSA | 55.56000 |
| LogP | 2.36 |
| Appearance | Â solid; White to Almost white powder to crystal |
| Vapour Pressure | 0.0±0.8 mmHg at 25°C |
| Refractive index | 1.543 |
| Storage conditions | Room temperature, sealed |
| Water solubility | Soluble in: ether, methanol, benzene, chloroform |
Description
Procaine can exert local anesthetic activity through multiple targets.
Procaine is a local anesthetic drug of the amino ester group, which acts through multiple targets.Target: OthersProcaine is a local anesthetic of the ester type that has a slow onset and a short duration of action.Procaine (0.01-100 microM) inhibited the 5-HT3 receptor-mediated inward current in the whole-cell patch clamp recording. Procaine appears to produce a competitive inhibition on 5-HT3 receptors with a KD of 1.7 microM .